MEGA 12 for Windows OS is now available.

This release adds many performance and usability enhancements as well as bug fixes.

MEGA 12: fast, filtered, substitution model selection

Filtering approach that avoids computations for sub-optimal substitution models.

MEGA 12: ML adaptive bootstrap

Adaptive bootstrap for Maximum Likelihood search to dynamically determine the number of replicates needed.

MEGA 12: DrPhylo for testing the fragility of inferred clades.

The DrPhylo application has been integrated with MEGA12 for investigating fragile species releationships.

Sophisticated and user-friendly software suite for analyzing DNA and protein sequence data from species and populations.

Redesigned Tree Explorer toolbar

The Tree Explorer toolbar has been updated to be more intuitive and accessible.

MEGA Software Celebrates Silver Anniversary

In the past 25 years, the MEGA software has been downloaded more then 3.5 million times.

Instructional Videos Now Available

Learn how to use MEGA from video tutorials created by MEGA users.

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Sequence Analyses
  • Phylogeny Inference
  • Model Selection
  • Dating and Clocks
  • Ancestral States
  • Selection and Tests
  • Sequence Alignment
Statistical Methods
  • Maximum Likelihood
  • Distance Methods
  • Ordinary Least Squares
  • Maximum Parsimony
  • Composite Likelihood
  • Bayesian
Powerful Visual Tools
  • Alignment/Trace Editor
  • Tree Explorer
  • Data Explorers
  • Legend Generator
  • Gene Duplication Wizard
  • Timetree Wizard