MantisBT - MEGA
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0001555MEGA[All Projects] Feedbackpublic2019-11-10 22:432019-11-11 11:21
guest 
gstecher 
normalminorhave not tried
resolvedunable to reproduce 
MEGA 11 (Graphical Interface version) 
 
Matheus
Araújo
matheus_araujo88@hotmail.com
matheus_araujo88@hotmail.com
0001555: Problem with the program using MacBook Air
Hello,

I'm using the MEGA X for MacBook Air, but I'm having some problems to use it. Comparing with my advisor, who uses the program in version 7.0 for Windows, is very different and many times some functions don't work in Mac (for example, pasting many sequences together after organized it, I can open just one archive at a time, and I need to put all together). I tried to install the old version, but it doesn't work too. What can I do?

Thank you so much!

Best Regards,

Matheus Araújo
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Issue History
1969-12-31 17:33Nikita VikhrevStatusassigned => resolved
1969-12-31 17:33Nikita VikhrevResolutionopen => fixed
2019-11-10 22:43guestNew Issue
2019-11-11 10:04gstecherFile Deleted: mle.zip
2019-11-11 11:21gstecherNote Added: 0004331
2019-11-11 11:21gstecherStatusnew => resolved
2019-11-11 11:21gstecherResolutionopen => unable to reproduce
2019-11-11 11:21gstecherAssigned To => gstecher

Notes
(0001350)
user19   
1969-12-31 17:33   
Data type = Nucleotide
Protein Coding = NO
File = Attached

Error:
Type = #/0
File = MLModels.pas
Object = TGTRModel
Function = SetParamsFromSeqs
Line = Fi[i] := 1/sqrt(FFreq[i])
(0001355)
agasky   
1969-12-31 17:33   
Dan, since you commented on this an apparently investigated it, please assign the bug to yourself.
(0001365)
Nikita Vikhrev   
1969-12-31 17:33   
This is not easy to be fixed. I am not sure whether GTR model is applicable to this data. I will think about it.
(0001368)
user19   
1969-12-31 17:33   
The problem turned out to be that MEGA wasn\'t supporting RNA. In the attached file there were no \'T\' characters, only \'U\'. Since it counted 0 \'T\' characters and we eventually got to a line where we divided by the frequency of \'T\' (which is 0) we got a div by 0 error.

I added support so that \'U\' is threated the same as \'T\'. We still need to fix the function SetParamsFromSeqs so that if we have 0 \'A\', \'T or U\', \'C\', or \'G\' then it doesn\'t continue and cause a div by 0 error.
(0001375)
Nikita Vikhrev   
1969-12-31 17:33   
Yet, we have to support the cases where frequencies of some nucleotide is really zero.
(0001376)
Nikita Vikhrev   
1969-12-31 17:33   
I have solve the problem all. I will send you the code after I return (I am out of town now).
(0004331)
gstecher   
2019-11-11 11:21   
Hi Matheus,

I am writing in response to your question regarding the MEGA software. If you are having issues running MEGA X on your mac system, you could try downloading the MEGA7 version for Windows and running it in a virtual machine (you could use something like VMWare Fusion or Parallels).

--
Best regards,
Glen Stecher
Institute for Genomics and Evolutionary Medicine
igem.temple.edu