MantisBT - MEGA
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IDProjectCategoryView StatusDate SubmittedLast Update
0001781MEGA[All Projects] Feedbackpublic2020-02-17 16:332020-03-06 08:12
Reporterguest 
Assigned Togstecher 
PrioritynormalSeverityminorReproducibilityhave not tried
StatusresolvedResolutionunable to reproduce 
PlatformOSOS Version
Product Version 
Target VersionFixed in Version 
First NameWaring
Last NameTrible
Emailbucktrible@gmail.com
Confirm Emailbucktrible@gmail.com
Summary0001781: OS X 64 bit download broken
DescriptionHi, I'm trying to download MEGAX for OS X, but the download link appears to be broken! I've tried on both Safari and Chrome; the automatic download doesn't work, and clicking the link to start the download takes me to a blank page with the following text:

/var/www/html/megasoftware.net/public_html/releases/releases

If you could provide me a .dmg that would be awesome!

Thanks for all of the great work you do.

Buck
Steps To Reproduce
Additional Information
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Issue History
Date ModifiedUsernameFieldChange
1969-12-31 17:33agaskyNote Added: 0001545
1969-12-31 17:33agaskyStatusnew => assigned
1969-12-31 17:33agaskyAssigned To => agasky
1969-12-31 17:33agaskyNote Added: 0001546
1969-12-31 17:33agaskyStatusassigned => feedback
1969-12-31 17:33agaskyFile Deleted: test2.meg
1969-12-31 17:33agaskyFile Added: test2_origional.meg
1969-12-31 17:33agaskyFile Added: test1.meg
1969-12-31 17:33agaskyFile Added: test2.meg
1969-12-31 17:33agaskyFile Added: TN Distance.xls
1969-12-31 17:33agaskyFile Added: diff.png
1969-12-31 17:33agaskyFile Added: distance_difference_explination.PNG
1969-12-31 17:33agaskyNote Added: 0001547
1969-12-31 17:33agaskyNote Added: 0001548
1969-12-31 17:33agaskyStatusfeedback => resolved
1969-12-31 17:33agaskyResolutionopen => fixed
2020-02-17 16:33guestNew Issue
2020-02-24 07:58gstecherFile Deleted: TN Distance.xls
2020-02-24 07:58gstecherFile Deleted: test2.meg
2020-02-24 07:58gstecherFile Deleted: test2_origional.meg
2020-02-24 07:58gstecherFile Deleted: test1.meg
2020-02-24 07:59gstecherFile Deleted: diff.png
2020-02-24 07:59gstecherFile Deleted: distance_difference_explination.PNG
2020-03-06 08:12gstecherStatusnew => resolved
2020-03-06 08:12gstecherResolutionopen => unable to reproduce
2020-03-06 08:12gstecherAssigned To => gstecher

Notes
(0001545)
agasky   
1969-12-31 17:33   
Hello Amber Ha,

  In the bug report you submited about MEGA, you mentioned 3 files (test1.meg, test2.meg, excelfile.xls). Unfortunatley, I only recieved the file test2.meg, if you could email me test1.meg and the excel file, it would help me to better understand the issue.

  In your steps to reproduce the bug, you mention aligning the data; are you aligning test1 and test2 seperately? If so, different distance results are not unusual; since every sequence is taken into account during the alignment. Since test1 and test2 will likely have different alignments their distances will also be different.

Thanks,
  Nick
(0001546)
agasky   
1969-12-31 17:33   
User only included 1 of the 3 files they mentioned in their bug report. Waiting to hear back from them with the other two files. I don't know why they didn't just zip up all 3 of the files and upload them with the bug report.

  It sounds like the user has an initial data set (test1), aligns it, and performs the pairwise distance analyis on it and finds a distance of 0.5 for the first two sequences, then goes back to the alignment of test1, adds in more sequences, re-aligns, and re-analyses the new file with pairwise distances and gets a distances of 0.4 for the first two sequences. They think that it must be a bug because of the difference, I THINK (not confirmed) that the difference is simply that the alignments are different which accounts for the pairwise distance difference.
(0001547)
agasky   
1969-12-31 17:33   
Dear Nick,

Thank you for your prompt reply. I have attached another set of files which
is our real data for your comments. Please ignore the attachement in
previous mail.

Test1 and test2 are aligned separately but the sequences no.1 to 30 and
sample Test1 to 5 are the same in the two files. No.1 to 29 are reference
sequences and no. 30 is outgroup sequence. In our analysis, we usually
compared the genetic relationship in terms of the genetic distance of test
sample ("Test1 to 7" in blue in excel file) among reference sequences (no.1
to 29). Reference sequences are fixed all the time in different analysis. We
supposed that the relationship among reference sequences no.1 to 29 should
remain unchanged in between different distance analysis. Is it right?
However, recently, we observed that discrepancy (0000090:0000030% analysis) happened
after entering Test samples. Please refer to the excel file for detail,
discrepancy for the reference sequences that we are much concern are
highlighted in red. In the past, we usually got distance value of 8% for
(10,11), but when we analyse only Test sample 1 to 5. The distnace for
(10,11) changed to 5.9%. All sequences in file test1 and test2 are same
except two sequences (Test6 and Test7) more in file test1. We found that
dicrepancy can turn back when any data set containing sequences of "Test6 &
7", the value will go back to 8.0%. I'm not sure anything we may get wrong
because we are new user. We would be grateful if you could help us to solve
this problem.



Looking forward to your reply.

Best regards,
Amber
(0001548)
agasky   
1969-12-31 17:33   
Hello Amber,

  When I compared your two meg files (test1.meg & test2.meg) I noticed that the alignment for sequences 10-19, test1, test2, test3 were different between the files (see diff.png). Remember, using pairwise deletion, sites with gaps or ambiguities are removed (if necessary) so the alignment can effect which sites are used to determine the pairwise distance. The file test1.meg has 398 sites with no gaps while test2.meg has 396 sites with no gaps. For a reason of the discrepancy see distance_difference_explination.png.

Thanks,
  Nick