MantisBT - MEGA
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IDProjectCategoryView StatusDate SubmittedLast Update
0000292MEGA[All Projects] Feedbackpublic2016-10-26 01:582016-10-26 01:58
Reporterguest 
Assigned To 
PrioritynormalSeverityminorReproducibilityhave not tried
StatusnewResolutionopen 
PlatformOSOS Version
Product VersionMEGA 11 (Graphical Interface version) 
Target VersionFixed in Version 
First NameSean
Last NameJohnson
Emailseanrjohnson@gmail.com
Confirm Emailseanrjohnson@gmail.com
Summary0000292: Excessive memory usage
DescriptionI'm trying to generate a maximum likelihood tree from nucleotide sequences, but MEGA keeps filling up all of the available memory and then crashing. My computer has 48 GB of RAM, and there are 18 sequences in the alignment. I've tried on a different computer with similar results. I'm doing 1000 bootstraps, it seems to crash between 300 and 500. Tamura-Nei model, Gamma distributed rates among sites.Partial deletion 80%. My OS is windows 7.
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Date ModifiedUsernameFieldChange
2016-10-26 01:58guestNew Issue

Notes
(0000201)
Nikita Vikhrev   
1969-12-31 17:33   
This is an inherent problem of the Clustal algorithm. In short, Clustal is not suitable for long-sequence data: 12 kb is long enough to kill Clustal.
(0000229)
gstecher   
1969-12-31 17:33   
There is indeed a bug here. Supporting evidence was sent to Koichiro for debugging.
(0000288)
Nikita Vikhrev   
1969-12-31 17:33   
Fixed.