MantisBT - MEGA
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IDProjectCategoryView StatusDate SubmittedLast Update
0000447MEGA[All Projects] Feedbackpublic2017-05-02 19:272017-05-09 11:53
Reporterguest 
Assigned Togstecher 
PrioritynormalSeverityminorReproducibilityhave not tried
StatusresolvedResolutionno change required 
PlatformOSOS Version
Product VersionMEGA 11 (Graphical Interface version) 
Target VersionFixed in Version 
First NameCathy
Last NameChen
Emailchenbingjie1992@126.com
Confirm Emailchenbingjie1992@126.com
Summary0000447: cancer phylogeny
DescriptionI am using mega to build a cancer evolution tree.

I wonder if I can combine all the mutations we called as a new sort sequence, than infer phylogenetic trees, cause the human genome is large, and we only need the inforamation of thousands of mutations.

Thanks
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Issue History
Date ModifiedUsernameFieldChange
2017-05-02 19:27guestNew Issue
2017-05-09 11:53gstecherNote Added: 0003781
2017-05-09 11:53gstecherStatusnew => resolved
2017-05-09 11:53gstecherResolutionopen => no change required
2017-05-09 11:53gstecherAssigned To => gstecher

Notes
(0000357)
gstecher   
1969-12-31 17:33   
This problem is well known to us. Essentially the WINE implementation of the portions of the windows media api are incomplete and/or buggy. We should probably replace the AVI with a GIF when possible.
(0003781)
gstecher   
2017-05-09 11:53   
Hi Cathy,

I am writing in response to your question regarding the MEGA software. Yes, you can use MEGA to construct a phylogeny without using the entire human genome, provided that you have assembled your mutation data into a valid sequence alignment.

--
Best regards,

Glen Stecher
Institute for Genomics and Evolutionary Medicine
igem.temple.edu