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Hi Ivo,
I am writing in response to your question regarding the ClustalW implementation in MEGA. The version of ClustalW that is used in MEGA5 is the one described in the paper listed below:
Higgins D., Thompson J., Gibson T. Thompson J. D., Higgins D. G., Gibson T. J.
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.
Nucleic Acids Res. 22:4673-4680. (1994)
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Best regards,
Glen Stecher
Institute for Genomics and Evolutionary Medicine
igem.temple.edu |
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