MantisBT - MEGA
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IDProjectCategoryView StatusDate SubmittedLast Update
0000763MEGADocumentationpublic2018-05-08 21:102023-04-14 18:58
Reporterguest 
Assigned To 
PrioritynormalSeverityminorReproducibilityhave not tried
StatusnewResolutionopen 
PlatformOSOS Version
Product VersionMEGA 11 (Graphical Interface version) 
Target VersionFixed in Version 
First NameChirag
Last NameKrishna
Emailkrc3004@med.cornell.edu
Confirm Emailkrc3004@med.cornell.edu
Summary0000763: unable to reproduce example for selection test
DescriptionHi,

I am trying to reproduce the "Testing for Selection" example in online manual under "A Walk Through Mega". I used the HLA-3Seq.meg file as suggested and entered all parameters as instructed, but I did not obtain a significant p value- in fact, I obtained Prob = 1.000 and Stat = -0.101.

The tutorial says: "The difference in synonymous and non-synonymous substitutions should be significant at the 5% level". Please find attached a screenshot of the input parameters I used for the selection test.

Any tips would be much appreciated- I'm very much looking forward to using MEGA for my analysis but want to ensure that I'm reproducing a simple example correctly. Thank you very much for your help!

Best,
Chirag
Steps To ReproduceDownloaded Mac version (GUI) of MEGA, ran selection test example at https://www.megasoftware.net/web_help_7/helpfile.htm#hc_first_time_user.htm [^]

"A Walk Through Mega" --> "Testing for Selection"

I am running macOS Sierra, Version 10.12.6
Additional InformationPlease find attached a screenshot of the input parameters I used for the selection test
TagsNo tags attached.
Relationships
Attached Files? selection-test.tiff (95,076) 2018-05-08 21:10
https://megasoftware.net/mantis_bt/
Issue History
Date ModifiedUsernameFieldChange
2018-05-08 21:10guestNew Issue
2018-05-08 21:10guestFile Added: selection-test.tiff
2022-03-13 06:34guestNote Added: 0005348
2022-03-13 07:23guestNote Added: 0005506
2023-04-14 18:58guestNote Added: 0006739

Notes
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