MEGA 12 (BETA) for Windows OS is now available.

This release adds many performance and usability enhancements as well as bug fixes.

MEGA 12: fast, filtered, substitution model selection

Filtering approach that avoids computations for sub-optimal substitution models.

MEGA 12: ML adaptive bootstrap

Adaptive bootstrap for Maximum Likelihood search to dynamically determine the number of replicates needed.

Sophisticated and user-friendly software suite for analyzing DNA and protein sequence data from species and populations.

MEGA 11: Molecular Evolutionary Genetics Analysis version 11

Version 11 adds new timing methods and is optimized for working with larger data.

MEGA 11 introduces expanded relaxed-clock dating methods

Calibration densities, tip dating, and a rate auto-correlation test have been added to MEGA.

Memory efficiency of the ML system has been improved

The Maximum Likelihood system has been optimized for memory efficiency in version 11.

Expanded group definitions

The MEGA file format now supports grouping taxa by geo/temporal designations.

Redesigned Tree Explorer toolbar

The Tree Explorer toolbar has been updated to be more intuitive and accessible.

MEGA Software Celebrates Silver Anniversary

In the past 25 years, the MEGA software has been downloaded more then 3.5 million times.

Instructional Videos Now Available

Learn how to use MEGA from video tutorials created by MEGA users.

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Sequence Analyses
  • Phylogeny Inference
  • Model Selection
  • Dating and Clocks
  • Ancestral States
  • Selection and Tests
  • Sequence Alignment
Statistical Methods
  • Maximum Likelihood
  • Distance Methods
  • Ordinary Least Squares
  • Maximum Parsimony
  • Composite Likelihood
  • Bayesian
Powerful Visual Tools
  • Alignment/Trace Editor
  • Tree Explorer
  • Data Explorers
  • Legend Generator
  • Gene Duplication Wizard
  • Timetree Wizard