0000347: Reltime multi-species outgroup clade

Notes
(0000241) gstecher (administrator) 1969-12-31 17:33	I need to add a redirect to the MEGA website so users don\'t get confused by the 404 error message.

(0000263) gstecher (administrator) 1969-12-31 17:33	Our Westhost account is currently screwed up so I cant get the access I need to fix this. I\'ll fix it when access is restored.

(0000266) gstecher (administrator) 1969-12-31 17:33	Fixed.

(0003730) gstecher (administrator) 2016-12-22 15:08	Hi Nitish, I am writing in response to your question regarding the Reltime analysis in MEGA. You are not doing anything wrong. By default, MEGA compresses the outgroup for the Reltime analysis. According to the appnote paper describing the release of MEGA7: "It is important to note that MEGA7 does not use calibrations that are present in the clade containing the outgroup(s), because that would require an assumption of equal rates of evolution between the ingroup and outgroup sequences, which cannot be tested. For this reason, timetrees displayed in the Tree Explorer have the outgroup cluster compressed and grayed out by default to promote correct scientific analysis and interpretation." If you are using the GUI version of MEGA, you can uncompress the outgroup using the formatting tools on the left toolbar. -- Best regards, Glen Stecher Institute for Genomics and Evolutionary Medicine igem.temple.edu

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