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IDProjectCategoryView StatusDate SubmittedLast Update
0000441MEGA[All Projects] Feedbackpublic2017-04-25 02:412024-04-17 02:41
Reporterguest 
Assigned To 
PrioritynormalSeverityminorReproducibilityhave not tried
StatusnewResolutionopen 
PlatformPCOSLinux 
Product VersionMEGA-CC 11 (command line version) 
Target VersionFixed in Version 
Summary0000441: MEGA-CC is very slow when using Bootstrap
DescriptionWhen doing Phylogeny Reconstruction, MEGA-CC is very slow when using Bootstrap in Neighbor-joining (~20s). The GUI version on MEGA is very fast (<1s)

An example data containing alignments of four DNA sequences is attached.

The result is:
No. Bootstrap Running time(s)
None 0.046
50 2.578
100 5.114
200 10.179
500 25.374




Steps To ReproducePlatform: CentOS 6.9, x86_64
Data: see attached file
MAO: see below

=========== infer_NJ_nucleotide.mao =============
; Please do not edit this file! If this file is modified, results are unpredictable.
; Instead of modifying this file, simply create a new MEGA Analysis Options file by using the MEGA Prototyper.
[ MEGAinfo ]
ver = 7160929-x86_64 Linux
[ DataSettings ]
datatype = snNucleotide
containsCodingNuc = False
MissingBaseSymbol = ?
IdenticalBaseSymbol = .
GapSymbol = -
[ ProcessTypes ]
ppInfer = true
ppNJ = true
[ AnalysisSettings ]
Analysis = Phylogeny Reconstruction
Scope = All Selected Taxa
Statistical Method = Neighbor-joining
Phylogeny Test = Not Applicable
Test of Phylogeny = Bootstrap method
No. of Bootstrap Replications = 500
Substitution Model = ====================
Substitutions Type = Nucleotide
Model/Method = Jukes-Cantor model
Substitutions to Include = All
Rates and Patterns = ====================
Rates among Sites = Uniform Rates
Gamma Parameter = Not Applicable
Pattern among Lineages = Same (Homogeneous)
Data Subset to Use = ====================
Gaps/Missing Data Treatment = Pairwise deletion
Site Coverage Cutoff (%) = Not Applicable
Has Time Limit = False
Maximum Execution Time = -1

Running command:
megacc -a infer_NJ_nucleotide.mao -d all.fasta -o all.nwk
TagsNo tags attached.
Attach Tags (Separate by ",")
First NameTao
Last NameZhu
Emailzhutao@caas.cn
Confirm Emailzhutao@caas.cn
Attached Files? file icon all.fasta (5,760 bytes) 2017-04-25 02:41

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-  Notes
(0000352)
gstecher (administrator)
1969-12-31 17:33

Forwarded to Sudhir
(0005877)
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2023-04-14 18:36

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- Issue History
Date Modified Username Field Change
2017-04-25 02:41 guest New Issue
2017-04-25 02:41 guest File Added: all.fasta
2022-12-05 06:55 guest Note Added: 0005877
2023-04-14 18:36 guest Note Added: 0006464
2024-04-17 02:40 guest Tag Attached: mega
2024-04-17 02:41 guest Tag Detached: mega


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